For more information, visit: https://www.miltenyibiotec.com/DEen/... The liver is a very good example of how tissue architecture can influence aging. Composed mainly of hepatocytes, the position of these cells is key to their role and determines changes in their metabolism and aging profile.

Researchers from the Max Planck Institute have used a novel perfusion technique for obtaining viable and functional hepatocytes from resected liver using the gentleMACS™ Technology. Afterwards, they have conducted an indepth multiomics analysis of functional and healthy hepatocytes, characterizing transcriptional, epigenetic, lipidomic and functional signatures to understand the effects of aging.

Liver perfusion technology is a novel technique that allows researchers to obtain viable hepatocytes in an easy and reproducible manner. It requires minimal training and effort, and yields highly viable hepatocytes that can be used downstream in any application.

Miltenyi Biotec is a global provider of products and services that empower biomedical discovery and advance cellular therapy. Our innovative tools support research at every level, from basic research to translational research to clinical application. This integrated portfolio enables scientists and clinicians to obtain, analyze, and utilize the cell. Our technologies offer solutions for cellular research, cell therapy, and cell manufacturing. Our more than 30 years of expertise spans research areas including immunology, stem cell biology, neuroscience, cancer, hematology, and graft engineering. In our commitment to the scientific community, we also offer comprehensive scientific support, consultation, and expert training. Today, Miltenyi Biotec has more than 4,700 employees in 23 countries – all dedicated to helping researchers and clinicians around the world make a greater impact on science and health.